Peptide synthesis

Peptide modification
Contact us
Shanghai Science Peptide Biological Technology Co.,Ltd
No.8 Changyang Road Shanghai 200082 P.R.China
Tel:021-51099675
http://www.scipeptide.com
Email:info@scipeptide.com
　
　


Custom Peptide Synthesis

1. Linear peptide, the length is up to 120aa, including GMP manufacturing and API processing optimization

2. Fluorescent labeling, including
a. Large- stock- shift dyes or dye- loaded nanoparticles with well-separated Ex and Em windows ;
b. Three types of Cyanine dyes (CY3, CY5, CY5.5, Cy7), including fluorescent nanoparticles; traditional unsymmetrical series; Novel symmetric cyanine dyes with super-solubility in aqueous solution, etc.
c. Super Alexa series (includingEm488 647, 750nm; Similar optical property as Invitrogen Alexa series, but better solubility)
d. C-terminal activatable labeling (Coumarin, CresylVilolet, Rhodamine110, etc);
e. FRET dyes, including “big dyes”, Cy3-Cy5 FRET, Cy5-Rhodamine 110, Fluorophore-Quencher Pairs, EDANS/DABCYL, MCA/DNP, Abz/DNP, Abz/Tyr(3-NO2), 5-FAM/TQ2, 5-TAMRA/QSY-7, 5-TAMRA/TQ3.
f. Others, including FITC, 5-FAM, 5-Iodoacetamido fluorescein, Texas Red, Farnesyl, Bodipy dyes, Oregon green series, GFP, etc

3. Luminescent labeling, including
a. Luciferin
b. CDP-Star
c. Luminol or isoluminol
d. Other luminescent substrates

4. N-Terminal modifications, including
Acetylation, Fatty acids, Fmoc, Boc, Bromoacetyl, Chloroacetyl, Benzoyl (Bz), Benzyloxycarbonyl (Z or CBZ), Formylation, Allyl, Alloc, Lipoic acid, Maleoyl-Beta-Ala, Suc; Biotin;

5. C-Terminal modifications, including
Amidation, -CHO, -OL, CMK, CFK, Cya, AMC, AFC, -OMe, -OEt, -OBzl, -TBzl, Pegylation, Fluorescent labeling, Lys(Biotin), Avidin, streptavidin, Neutravidin, Antibody or antibody fragment,

6. Carrier Proteins, including KLH, BSA and OVA

7. Side Chain Modifications, including
a. Phosphorylation (multiple, including Ser, Thr, and Tyr; can be (
b. Mannosylation (multiple,including Ser, Thr, and Tyr; can be (
c. Acetylation, methylation (Mono-, Bis-, and triple) on lysine(s);
d. Sulfonation and Glycosylation
e. Esterification (C(O)-O, O and S)

8. Anywhere in the peptides, including
a. Special amino acids: D-format amino acids, homo-amino acids, Amino Butyric Acid (Abu), Beta-Alanine, Methylation (Lys and Arg), Ser (octanoic acid), Tyrosine(SO3), etc.
b. Mini-PEG
c. Peptide linkers, such as Ahx, Ava, GABA, Beta-Ala
d. Isotopes modification, such as N15 and C13

9. Peptides with advanced structures, including
a. MAPs,
b. Cyclic peptide, including mono, double and triple and disulfide bridges; head to tail bridge; Head/Tail-side bridge
c. Peptide amphiphile with more than one hydrophobic tails

11. Super-Hydrophobic peptides

12. Special peptide design and peptide synthesis for antibody production, enzyme substrates and peptide microarray, etc.

13. Peptide-related molecular imaging/therapeutic reagent, including
a. Ligand-rare-earth element complex (DTPA, EDTA ligand with Eu, Ln ) or other imaging contrast reagents (i.e. MRI, nuclear imaging, etc) conjugated with peptides;
b. Therapeutic reagents , such as PDT (Photo-Dynamic therapy) reagents with peptide as targeting moiety;
c. Nanoparticle or polymeric carrier based diagnostic/therapeutic reagents with peptide as targeting moiety;
d. Therapeutic peptides conjugated with targeting moiety, such as antibody, affibody, sugar, growth factors, etc.

14. Peptide Kits development, including design, component synthesis and assembly, testing and optimization.

15. Other related service, switching salt (Acetate salt and HCL salt form), N element analysis, Amino Acid Analysis (AAA), solubility, etc.
　

Please fill out all the required fields of this form to receive a prompt quotation on your peptide.

　
Sequence:               
 AlanineAlaA
 AsparagineAsnN
 Glutamic acidGluE
 GlycineGlyG
 IsoleucineIleI
 LysineLysK
 PhenylalaninePheF
 SerineSerS
 TryptophanTrpW
 ValineValV
 		 ArginineArgR
 CysteineCysC
 Glutamine GlnQ
 HistidineHisH
 LeucineLeuL
 MethionineMetM
 ProlineProP
 ThreonineThrT
 TyrosineTyrY
 Aspartic acidAspD
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